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Yoshiaki Nakamura Selected Research

Stomach Neoplasms (Stomach Cancer)

6/2022Multicenter phase II trial of trastuzumab deruxtecan for HER2-positive unresectable or recurrent biliary tract cancer: HERB trial.
1/2022Updated Efficacy Outcomes of Anti-PD-1 Antibodies plus Multikinase Inhibitors for Patients with Advanced Gastric Cancer with or without Liver Metastases in Clinical Trials.
12/2021Hypothyroidism and hypopituitarism as immune-related adverse events due to lenvatinib plus pembrolizumab therapy in the immediate postoperative period after laparoscopic hepatectomy for liver metastases from gastric cancer: a case report.
10/2021Circulating Tumor DNA Analysis Detects FGFR2 Amplification and Concurrent Genomic Alterations Associated with FGFR Inhibitor Efficacy in Advanced Gastric Cancer.
3/2021The Right Treatment of the Right Patient: Integrating Genetic Profiling Into Clinical Decision Making in Advanced Gastric Cancer in Asia.
1/2021A multicenter phase II study of TAS-114 in combination with S-1 in patients with pretreated advanced gastric cancer (EPOC1604).
1/2020The Impact of Molecular Subtype on Efficacy of Chemotherapy and Checkpoint Inhibition in Advanced Gastric Cancer.
1/2020Correction to: Epigenetic priming sensitizes gastric cancer cells to irinotecan and cisplatin by restoring multiple pathways.
1/2020Lenvatinib plus pembrolizumab in patients with advanced gastric cancer in the first-line or second-line setting (EPOC1706): an open-label, single-arm, phase 2 trial.
1/2020Epigenetic priming sensitizes gastric cancer cells to irinotecan and cisplatin by restoring multiple pathways.
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Yoshiaki Nakamura Research Topics

Disease

41Neoplasms (Cancer)
10/2022 - 03/2011
21Stomach Neoplasms (Stomach Cancer)
06/2022 - 01/2018
19Colorectal Neoplasms (Colorectal Cancer)
10/2022 - 11/2018
11Breast Neoplasms (Breast Cancer)
01/2022 - 01/2003
8Neoplasm Metastasis (Metastasis)
01/2022 - 02/2015
5Microsatellite Instability
01/2022 - 11/2018
5Gastrointestinal Neoplasms (Gastrointestinal Cancer)
11/2021 - 01/2020
4Disease Progression
01/2022 - 01/2003
2Fever (Fevers)
12/2021 - 01/2018
2Colonic Neoplasms (Colon Cancer)
07/2021 - 01/2017
2Neutropenia
01/2021 - 12/2019
2Residual Neoplasm
12/2020 - 01/2019
2Triple Negative Breast Neoplasms
01/2019 - 07/2012
1Biliary Tract Neoplasms (Biliary Tract Cancer)
06/2022
1Lymphatic Metastasis
04/2022
1Amyloid Plaque
01/2022
1Alzheimer Disease (Alzheimer's Disease)
01/2022
1Adenocarcinoma
01/2022
1Hypoxia (Hypoxemia)
01/2022
1Adrenal Insufficiency (Adrenal Gland Hypofunction)
12/2021
1Fatigue
12/2021
1Hypopituitarism (Sheehan's Syndrome)
12/2021
1Hypothyroidism
12/2021
1Cholangiocarcinoma
10/2021
1Exanthema (Rash)
01/2021
1Lymphopenia (Lymphocytopenia)
01/2021
1Anemia
01/2021
1Thrombocytopenia (Thrombopenia)
01/2021
1Necrosis
12/2020

Drug/Important Bio-Agent (IBA)

14Circulating Tumor DNAIBA
04/2022 - 11/2018
9Biomarkers (Surrogate Marker)IBA
04/2022 - 11/2018
7Immune Checkpoint InhibitorsIBA
09/2022 - 11/2018
6pembrolizumabIBA
01/2022 - 01/2020
6Trastuzumab (Herceptin)FDA Link
01/2022 - 12/2010
5human ERBB2 proteinIBA
01/2022 - 11/2014
5NivolumabIBA
01/2022 - 01/2019
4Monoclonal AntibodiesIBA
06/2021 - 01/2019
4Irinotecan (Camptosar)FDA LinkGeneric
06/2021 - 01/2020
4Hormones (Hormone)IBA
01/2018 - 01/2016
3ErbB Receptors (EGF Receptor)IBA
01/2022 - 11/2018
3lenvatinibIBA
01/2022 - 01/2020
3trifluridine tipiracil drug combinationIBA
07/2021 - 12/2019
3Oxaliplatin (Eloxatin)FDA LinkGeneric
07/2021 - 02/2019
3Paclitaxel (Taxol)FDA LinkGeneric
01/2018 - 12/2010
2trastuzumab deruxtecanIBA
06/2022 - 01/2021
2regorafenibIBA
01/2022 - 01/2021
2Formaldehyde (Formol)FDA Link
01/2022 - 01/2018
2ParaffinIBA
01/2022 - 01/2018
2pertuzumabIBA
01/2022 - 11/2021
2Tumor Biomarkers (Tumor Markers)IBA
10/2021 - 07/2021
2Capecitabine (Xeloda)FDA Link
07/2021 - 02/2019
2Cell-Free Nucleic AcidsIBA
03/2021 - 12/2019
2Bevacizumab (Avastin)FDA Link
01/2021 - 12/2019
2Estrogen ReceptorsIBA
01/2021 - 11/2014
2Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2019
2DNA (Deoxyribonucleic Acid)IBA
01/2020 - 01/2020
2Taxoids (Taxanes)IBA
01/2020 - 09/2017
2Cisplatin (Platino)FDA LinkGeneric
01/2020 - 01/2020
2AnthracyclinesIBA
09/2017 - 03/2012
2Aromatase InhibitorsIBA
11/2016 - 03/2011
1Notch ReceptorsIBA
10/2022
1Pharmaceutical PreparationsIBA
06/2022
1Amyloid (Amyloid Fibrils)IBA
01/2022
1CateninsIBA
01/2022
1Mechanistic Target of Rapamycin Complex 1IBA
01/2022
1Vitamin DFDA LinkGeneric
01/2022
1AntibodiesIBA
01/2022
1hydroxide ionIBA
01/2022
1Hematoxylin (Haematoxylon)IBA
01/2022
1Eosine Yellowish-(YS) (Eosin)IBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1Hydrocortisone (Cortisol)FDA LinkGeneric
12/2021
1Docetaxel (Taxotere)FDA Link
12/2021
1Blood Glucose (Blood Sugar)IBA
12/2021
1Thyroxine (Levothyroxine)FDA LinkGeneric
12/2021
1Small Cytoplasmic RNAIBA
11/2021
1Programmed Cell Death 1 ReceptorIBA
10/2021
1Panitumumab (Vectibix)FDA Link
06/2021
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2021
1DeoxyuridineIBA
01/2021
1dUTP pyrophosphataseIBA
01/2021
1fms-Like Tyrosine Kinase 3IBA
01/2021
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2021
1TAS-114IBA
01/2021
1Phosphotransferases (Kinase)IBA
01/2020

Therapy/Procedure

28Therapeutics
01/2022 - 01/2003
15Drug Therapy (Chemotherapy)
10/2022 - 12/2010
8Precision Medicine
01/2022 - 09/2018
5Adjuvant Chemotherapy
12/2021 - 09/2017
3Immunotherapy
01/2022 - 01/2019
3Hepatectomy
12/2021 - 05/2002
2Neoadjuvant Therapy
01/2022 - 01/2019
2Molecular Targeted Therapy
01/2022 - 01/2022
2Gastrectomy
12/2021 - 02/2019
2Genomic Medicine
02/2021 - 09/2018
1Lymph Node Excision (Lymph Node Dissection)
04/2022
1Aftercare (After-Treatment)
04/2022
1Transplantation
01/2021
1Combination Drug Therapy (Combination Chemotherapy)
01/2020
1Radiotherapy
01/2020